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Fig. 2 | BMC Neuroscience

Fig. 2

From: Thrombin contributes to the injury development and neurological deficit after acute subdural hemorrhage in rats only in collaboration with additional blood-derived factors

Fig. 2

The local CBF was not affected by the PAR1-antagonist SCH 79797 after ASDH (left graph). CBF was stable during the baseline period (32.6 ± 0.5 LDU, mean ± SEM). In the second minute after ASDH induction CBF dropped down and was constantly significant underneath the sham-operated animals (**SCH-1 vs. sham P < 0.001; **SCH-5 vs. sham P < 0.001; **vehicle vs. sham P < 0.001). Local administration of the PAR1 antagonist SCH79797 results in a not significantly reduced neuronal damage 14 days after ASDH compared to vehicle treatment, similar to the Argatroban treatment (right graph)

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BMC Neuroscience

ISSN: 1471-2202

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