Author, year | Mean age | Participants (M/F) | Intervention | Stimulation site | Frequency, duration and intensity | Outcomes |
---|---|---|---|---|---|---|
Han, 2013 | 66.59 | 40 (14/26) | T: active rTMS C: sham rTMS | Left/right DLPFC | 20Â Hz, 80% RMT, 30Â min/day, 5Â days/week, 8Â weeks | Global cognitive function/MoCA; Linguistic function/VFT; Executive function/WCST; Attention/TMT-A, DSST |
Zhang, 2014 | 65.75 | 50 (25/25) | T: active rTMS C: oral Piracetam | Bilateral frontal area | 5Â Hz, 100% RMT, 800 pulses/day, 6Â days/week, 16Â weeks | Global cognitive function/MoCA; ERP |
Yang, 2014 | 66.00 | 33 (15/18) | T: active rTMS C: sham rTMS | Bilateral DLPFC | 20Â Hz, 80% RMT, 30Â min/day, 5Â days/week, 8Â weeks | Global cognitive function/MMSE; ERP |
Rosa, 2015 | 69.05 | 20 (11/9) | T: anode tDCS + PT C: sham tDCS + PT | Left DLPFC | 2 mA, 25 min/day, 5 days/week, 2 weeks | Global cognitive function/MMSE, PD-CRS; Memory/PAL; Attention/TMT; Executive function/Semantic fluency |
Sun, 2015 | 64.40 | 80 (43/37) | T: active rTMS + cognitive training C: cognitive training | Left DLPFC and left PC | 15 Hz, 80%-110%RMT, 30 min/day, 6 days/week, 8 weeks | Global cognitive function/MoCA; ERP |
Hellen, 2015 | 65.16 | 34 (12/22) | T: active rTMS C: sham rTMS | Left DLPFC | 10Â Hz, 110% RMT, 2000 pulses/session, 1 session/day, 10Â days | Memory/RBMT, WMS, RAVLT, WAIS-III; Executive function/TMT-B, VFT |
Kyongsik, 2016 | 73.94 | 16 (5/11) | T: anode tDCS C: sham tDCS | Anodal: left DLPFC; Cathode: right DLPFC | 2Â mA, 30Â min/day, 3Â days/week, 3Â weeks | Memory/MMQ, HVLT; Visuospatial function/RCFT; Linguistic function/BNT; PET |
Long, 2016 | 66.95 | 30 (14/16) | T: active rTMS C: sham rTMS | Left DLPFC | 15Â Hz, 90% RMT, once a day, 10Â days | Global cognitive function/MoCA; Memory/CMS |
Wu, 2017 | 67.61 | 41 (21/20) | T: active rTMS + oral paroxetine C: oral paroxetine | Left DLPFC | 20 Hz, 80% RMT, 15 min/day, 5 days/week, 4 weeks | Global cognitive function/MMSE; ERP |
Giacomo, 2017 | 70.00 | 14 (7/7) | T: active rTMS C: sham rTMS | PC | 20Â Hz, 100% RMT, 20Â min/day, 5Â days/week, 6Â weeks | Global cognitive function/MMSE, Memory/RAVLT; Executive functions/FAB; Attention/DSST |
Prasad, 2018 | 65.60 | 9 (8/1) | T: active rTMS C: sham rTMS | Left DLPFC | 10Â Hz, 120% RMT, 45Â min/day, 5Â days/week, 8Â weeks | Apathy/AES-C; Global cognitive function/MMSE; Executive functions/TMT A&B; Functional status/IADL; Impression/CGI |