Fig. 2
From: Gastrodin protects dopaminergic neurons via insulin-like pathway in a Parkinson’s disease model
Gastrodin can alleviate the injury of dopamine neurons and accumulated α-synuclein in two PD models. a Both 50 and 100 μM gastrodin restored the loss of GFP of dopaminergic neurons with 6-OHDA treatment. b Quantification of dopaminergic neurons in C. elegans using Image J software by one-way ANOVA. (The scale bar and magnification of left panel is 50 μm, 200; The scale bar and magnification of right panel is 25 μm, 400, respectively). c Gastrodin markedly lessened GFP of α-synuclein in the PD model with overexpressed α-synuclein. d The fluorescence intensity of α-synuclein was also analyzed by Image J. (The scale bar and magnification of left panel is 200 μm, 40; The scale bar and magnification of right panel is 100 μm, 100). The used statistical differences were t-test. ns P ≥ 0.05; *P < 0.05; **P < 0.01; ***P < 0.001