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Fig. 8 | BMC Neuroscience

Fig. 8

From: Altered excitability of small cutaneous nerve fibers during cooling assessed with the perception threshold tracking technique

Fig. 8

Cooling may increase understanding of abnormal ionic current during neuropathy. The Na/K-ATPase (0%), NaTTXr (130%), NaTTXs (500%) and NaP (200%) maximal conductances were altered to generate the hyperexcitability models. a The activation threshold estimated in the hyperexcitability models and the control model (no alteration of the ionic conductances) for the temperature condition 32 °C. b The activation threshold estimated in the hyperexcitability models and the control model (no alteration of the ionic conductances) for the temperature condition 20 °C. c The relative difference between the activation threshold for the two temperature conditions (20 °C and 32 °C)

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