Lipopolysaccharide worsens the prognosis of experimental cerebral ischemia via interferon gamma-induced protein 10 recruit in the acute stage

Table 4 The significantly enriched GO terms with a high count of different genes 4.5 h post-MCAO

Term	Category	Description	Count	P-value
GO:0006955	BP	Immune response	15	9.38E−15
GO:0006954	BP	Inflammatory response	12	7.31E−14
GO:0009611	BP	Response to wounding	12	8.33E−12
GO:0006952	BP	Defense response	12	1.30E−10
GO:0010604	BP	Positive regulation of macromolecule metabolic process	12	5.05E−09
GO:0045449	BP	Regulation of transcription	12	0.001056
GO:0010557	BP	Positive regulation of macromolecule biosynthetic process	11	1.44E−08
GO:0042127	BP	Regulation of cell proliferation	11	1.67E−08
GO:0031328	BP	Positive regulation of cellular biosynthetic process	11	2.13E−08
GO:0009891	BP	Positive regulation of biosynthetic process	11	2.32E−08
MF00016	MF	Signaling molecule	11	1.78E−07
GO:0001817	BP	Regulation of cytokine production	10	1.68E−12
GO:0005615	CC	Extracellular space	10	3.33E−08
GO:0010628	BP	Positive regulation of gene expression	10	1.13E−07
GO:0044421	CC	Extracellular region part	10	1.15E−06
GO:0005576	CC	Extracellular region	10	5.80E−04
GO:0006355	BP	Regulation of transcription, DNA-dependent	10	7.87E−04
GO:0051252	BP	Regulation of RNA metabolic process	10	8.82E−04
MF00017	MF	Cytokine	9	3.90E−12
GO:0045893	BP	Positive regulation of transcription, DNA-dependent	9	4.94E−07

GO Gene Ontology, BP biological process, CC cellular compartment, MF molecular function

ISSN: 1471-2202