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Table 6 Blood DML (p < 0.0001); PD cases with OGC pesticide exposure 4+ vs 0–2 detectable levels

From: Genome-wide epigenetic analyses in Japanese immigrant plantation workers with Parkinson’s disease and exposure to organochlorines reveal possible involvement of glial genes and pathways involved in neurotoxicity

PROBESET ID

CHR

CpG location

Gene name

p-value (Code 2 vs. 0)

Methylationa

cg09677945

13

5′UTR; 1stExon

DNAJC15

9.55E−06

+

cg12456927

4

Intergenic

 

1.10E−05

cg02598807

11

Body

AP2A2

1.94E−05

cg11667387

10

Body

CNNM2

2.03E−05

cg15723784

15

Body; Body; 5′UTR

SMAD3

2.18E−05

+

cg12363545

3

TSS200

CD47

3.24E−05

+

cg16004427

1

Intergenic

 

3.58E−05

+

cg17242362

7

Body

ATXN7L1

3.71E−05

+

cg12659981

5

TSS1500

ODZ2

4.06E−05

cg01047025

9

Body

DMRT1

4.26E−05

+

cg13904560

15

Body

GABRB3

4.53E−05

cg10574499

16

TSS200

NRN1L

4.87E−05

+

cg11910782

19

TSS1500

LEUTX

5.10E−05

cg10846328

2

Body

BIN1

5.33E−05

cg22859727

14

3′UTR

FLRT2

5.97E−05

+

cg26567712

19

TSS200

CCDC124

6.13E−05

+

cg00335735

2

Body

EPHA4

7.07E−05

+

cg10066684

X

TSS1500

TBC1D8B

9.91E−05

+

  1. a Hyper (+) or Hypo (−) methylation