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Table 8 Concordant genes with CpG SNPs associated with exposures in brain and blood

From: Genome-wide epigenetic analyses in Japanese immigrant plantation workers with Parkinson’s disease and exposure to organochlorines reveal possible involvement of glial genes and pathways involved in neurotoxicity

Contrast variable

Gene symbol

Probe Id

SNP at CpG

Methylationa

p-values

Brain

Blood

Plantation work

C1QTNF7

cg18075755

rs13116402

5.49E−04

3.28E−04

OGC

DNAJC15

cg19182537

rs2281781

+

7.56E−05

3.02E−04

OGC

CORO7

cg04395006

rs191030943

7.80E−04

1.41E−04

OGC

TMCO3

cg05608383

rs117368475

4.63E−04

1.72E−04

OGC

MPPED1

cg00740510

rs12483886

5.31E−04

9.12E−04

OGC

C14orf182

cg18709904

rs2355655

4.36E−04

9.25E−04

  1. a Observed as Hyper (+) or Hypo (−) methylation