Fig. 4

Western Blot Analysis. Reactivity against healthy control tissue and TDP-43 immunoprecipitated from healthy controls and FTD was assessed under non-reducing and non-denaturing conditions with (a) Commercial TDP antibody identifying TDP variants in FTD and healthy controls, and (b) FTD-TDP2 scFv which recognizes disease variant of TDP (~ 70 kDa) present in FTD and not healthy controls