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Table 1 Allocation of pigs to the 4 experimental groups

From: Neurologic effects of short-term treatment with a soluble epoxide hydrolase inhibitor after cardiac arrest in pediatric swine

Parameter

Total

Sham + Veh

Sham + TPPU

CA + Veh

CA + TPPU

Intent-to-treat

46

11

10

13

12

Did not complete 4 day protocol

12

3

1

4

4

Survived 4 day protocol

34

8

9

9

8

Reasons for death

     

 Could not be resuscitated

4

N/A

N/A

2

2

 Could not be extubated

3

2

0

0

1

 Poor perfusion after extubation

1

0

0

0

1

 Refractory seizures

1

0

0

1

0

 Severe hypotension prior to protocol initiation

2

1

0

1

0

 Other

1

0

1a

0

0

Asphyxia duration in 4 d survivors

 7 min

15

N/A

N/A

8

7

 8 min

2

N/A

N/A

1

1

Received ≥ 1 dose of vehicle/drug prior to death

6

2

1

1

2

  1. CA, cardiac arrest; N/A, not applicable; Veh, vehicle
  2. aDied suddenly after 2nd TPPU injection, likely secondary to venous air embolism
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BMC Neuroscience

ISSN: 1471-2202

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