Fig. 3From: Knockout of the circadian gene, Per2, disrupts corticosterone secretion and results in depressive‐like behaviors and deficits in startle responsesEffect of genotype on Mc2R and Hsd1 gene expression in the adrenal. Mice were restrained for 20 min (0–20 min; striped bar). There was no effect of genotype on Hsd1 expression in the adrenal. However, Mc2R expression increased in the adrenal immediately following restraint in Per2−/− mice, but not in WT mice. *p < 0.05 WT vs. respective Per2−/− time point. (n = 5–8 animals per group)Back to article page