Fig. 3
From: Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism
Anxiety and depressive-like behavior of wild-type (WT, blue) and Chd8+/∆SL (Chd8±, red) mice. The light–dark box (a–d). A test mouse started from the light zone. a Time spent in the light zone. b The number of entries to the dark zone. Reverse tests initiated from the dark zone. n = 5–7. c Time spent in the light zone when started from the dark zone. d The number of entries. e Elevated plus maze test. Bars represent time spent in the open arm for a 5-min period. f Tail suspension test. Bars represent immobility time. g Sucrose preference test. Bars represent the consumption ratio of 1% sucrose over water. Columns with different superscript letters (a–c) are significantly different at p < 0.05