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Fig. 5 | BMC Neuroscience

Fig. 5

From: MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer’s disease

Fig. 5

Spatial memory testing of male mice using the RAWM. SB-3CT and vehicle-treated male E4FAD mice were tested for their ability to find the hidden platform in the RAWM. A A schematic of the maze layout is displayed. Mice were tested in nine trials per day for 5 days. B The number of incorrect entries made and C the time taken to find the maze were recorded and analyzed. D The total distance travelled per trial and E the average velocity while swimming was also evaluated. Values represent mean ± SEM (N = 5 males for each group). No statistical significance was identified in any of the parameters by ANOVA. RAWM Radial arm water maze, E4FAD Apolipoprotein E4 x Familial Alzheimer’s disease, SEM Standard error of the mean, ANOVA Analysis of variance

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