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Fig. 7 | BMC Neuroscience

Fig. 7

From: MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer’s disease

Fig. 7

Analysis of LDLR and LRP1 levels in the cerebrovasculature and the soluble brain fraction. Levels of the A, B LDLR receptor and C, D LRP1 receptor were analyzed in the A, C soluble brain fraction and B, D the cerebrovasculature of SB-3CT and vehicle-treated E4FAD mice. Animals were approximately 5 months of age and values represent mean ± SEM (N = 14, 5 males, 9 females for each group). No statistically significant differences in LDLR or LRP1 levels were identified between vehicle or SB-3CT-treated mice in either brain fraction by ANOVA. LDLR Low-density lipoprotein receptor, LRP1 Low density lipoprotein receptor-related protein 1, E4FAD Apolipoprotein E4 x Familial Alzheimer’s disease, SEM Standard error of the mean, ANOVA Analysis of variance

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