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Fig. 1 | BMC Neuroscience

Fig. 1

From: In vivo oxygen measurement in cerebrospinal fluid of pigs to determine physiologic and pathophysiologic oxygen values during CNS infections

Fig. 1

Oxygen values in the CSF of pigs decrease rapidly over time after death. a The position of the needle inside the CSF compartment in the region of the Articulatio atlantooccipitalis is demonstrated with a halved carcass of a pig. 1 = Os occipitale, 2a = Atlas (Arcus dorsalis), 2b = Atlas (Arcus ventralis), 3a = Axis (Processus spinosus), 3b = Axis (Corpus), 4 = cerebrum (brain), 5 = Medulla spinalis (spinal cord), 6 = Cisterna cerebellomedullaris, 7 = Spatium atlantooccipitale, 8 = approximate position of the needle for CSF aspiration. b Computer tomography image of a catheter inserted through the Spatium atlantooccipitale into the Cisterna cerebellomedullaris and the subarachnoid space. White arrows mark the catheter. c Oxygen measurement system: Connected with a flexible tube to the needle located inside the CSF. Black arrows show CSF flow into the syringe. The dissolved oxygen is measured with the oxygen (O2) Flow-Through-Cell (FTC)-PSt7-sensor connected to the OXY-1 ST device. d Each symbol represents a freshly drawn CSF sample of one pig. Values of one pig are connected by a line, not reflecting constant measurement. The values depict a continuous decrease in oxygen over time after death with high variability

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