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Table 1 Mean ± standard deviation of respiratory rate (fr), fraction of inspired oxygen (FiO2), arterial partial pressure of oxygen paO2/FiO2 quotient (Horoviz quotient), tidal volume (VT), arterial partial pressure of CO2 (paCO2) and end tidal carbon dioxide (Pe´CO2) of uninfected, infected (CSF−S. suis) and infected (CSF + S. suis) pigs (nuninfected = 6, ninfected = 3 in each group) 13, 16 and 19 h post infection

From: In vivo oxygen measurement in cerebrospinal fluid of pigs to determine physiologic and pathophysiologic oxygen values during CNS infections

 

fr (breaths minute−1)

FiO2

paO2/FiO2 (mmHg)

Post infection

13 h

16 h

19 h

13 h

16 h

19 h

13 h

16 h

19 h

Uninfected

18.3 ± 2.3

18 ± 2.7

17.6 ± 3.6

0.34 ± 0.14

0.36 ± 0.06

0.33 ± 0.1

330 ± 40

275 ± 71

293 ± 89

Infected (CSF—S. Suis)

17.3 ± 3.2

18 ± 3

18 ± 3

0.25 ± 0.03

0.28 ± 0.04

0.28 ± 0.04

401 ± 64

359 ± 44

346 ± 44

Infected (CSF + S. Suis)

19 ± 1

19.7 ± 1.5

20.3 ± 1.2

0.28 ± 0.05

0.28 ± 0.01

0.29 ± 0.01

378 ± 52

342 ± 29

379 ± 75

 

VT (ml kg−1)

paCO2 (mmHg)

Pe´CO2 (mmHg)

Post infection

13 h

16 h

19 h

13 h

16 h

19 h

13 h

16 h

19 h

Uninfected

13.2 ± 2

14.3 ± 2.1

13.8 ± 2

42.8 ± 7.3

41 ± 3.6

41.6 ± 2.4

41.5 ± 6.3

40.5 ± 3.4

39.8 ± 3.1

Infected (CSF—S. Suis)

11.7 ± 2

12.2 ± 2.4

12.2 ± 2.4

38.1 ± 2.2

42.2 ± 4.7

45.2 ± 4.9

39.3 ± 0.6

40.7 ± 1.5

41.7 ± 3.1

Infected (CSF + S. Suis)

12.3 ± 2

12.3 ± 2.3

12.6 ± 0.4

47.7 ± 1.5

49.3 ± 3

45.3 ± 5.8

48.3 ± 0.6

48.7 ± 0.6

43.7 ± 3.5