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Fig. 2 | BMC Neuroscience

Fig. 2

From: Epileptiform activity in mouse hippocampal slices induced by moderate changes in extracellular Mg2+, Ca2+, and K+

Fig. 2

Measures for hippocampal ictal and interictal events of thin slices. Slices obtained from young (21–28 days old), middle-aged (13–14 months old) and aged (24–26 months old) mice. A Proportions of slices with or without epileptiform field potentials estimated from the three age groups. The “ictal” category refers to slices that displayed discharges spontaneously or following high frequency stimulation (HFS), irrespective of associated interictal spikes; the “interictal” refers to slices that expressed interictal spikes spontaneously or following HFS, but no spontaneous or HFS-induced ictal discharges; the “no” denotes slices that did not exhibit spontaneous nor HFS-induced epileptiform field potentials. B Interevent intervals of hippocampal interictal spikes measured in individual slices of the three age groups. C, D Interevent intervals and durations of ictal discharges measured in individual slices with ≥ 5 ictal events. Measures for slices of the middle-aged and aged groups were pooled. Box plots presented BD, and interquartile range abbreviated as IQR. *One-way analysis of variance (B) or Student t test (C), p < 0.05, median values comparison

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