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Fig. 3 | BMC Neuroscience

Fig. 3

From: Repair-related molecular changes during recovery phase of ischemic stroke in female rats

Fig. 3

ERK1/2 and Akt pathways are affected at day 14 after tMCAO. A Representative western blots of p-ERK1/2 and t-ERK1/2 for peri-infarct and ischemic core vs. contralateral samples. B Quantification of p-ERK1/2 (normalized to t-ERK1/2 and β-actin—left graph) and t-ERK1/2 (normalized to β-actin—right graph) in peri-infarct and ischemic core compared to contralateral. C Representative western blots of p-Akt and Akt for peri-infarct vs contralateral (left panel) and ischemic core vs contralateral (right panel). D Quantification of p-Akt (normalized to Akt and β-actin) in peri-infarct and ischemic core showed significant increase compared to their related contralateral samples (left graph). Akt expression was significantly lower in peri-infarct and ischemic core compared to contralateral (right graph). Number of animals for ischemic core; n = 7, number of animals for peri-infarct; n = 5. AU arbitrary units, *Significant differences (p < 0.05). The presented western blot images are cropped and the full-length blots/gels are presented in Additional file 2: Figure S1

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