Treatment (μg/mouse) | Latency to onset (sec) | Seizure duration (sec) | Seizure intensity (maximum score 5.0) |
---|---|---|---|
Vehicle | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
KA (0.2) alone | 169.9 ± 38.8* | 1,200.6 ± 372.3* | 4.2 ± 0.1* |
+MK (0.1) | 160.0 ± 28.5 | 616.7 ± 50.3# | 2.5 ± 0.3# |
+MK (0.2) | 172.8 ± 33.8 | 422.4 ± 71.5# | 2.2 ± 0.2# |
+MK (0.4) | 188.8 ± 47.0 | 318.6 ± 31.7# | 1.7 ± 0.3# |