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  1. Brain radiation exposure, in particular, radiotherapy, can induce cognitive impairment in patients, with significant effects persisting for the rest of their life. However, the main mechanisms leading to this ...

    Authors: Bo Xu Ren, Isaac Huen, Zi Jun Wu, Hong Wang, Meng Yun Duan, Ilonka Guenther, K. N. Bhanu Prakash and Feng Ru Tang

    Citation: BMC Neuroscience 2021 22:28

    Content type: Research article

    Published on:

  2. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Mara A. Guzmán-Ruiz, Amor Herrera-González, Adriana Jiménez, Alan Candelas-Juárez, Crystal Quiroga-Lozano, Claudia Castillo-Díaz, Erika Orta-Salazar, Diana Organista-Juárez, Sofía Díaz-Cintra and Rosalinda Guevara-Guzmán

    Citation: BMC Neuroscience 2021 22:27

    Content type: Correction

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    The original article was published in BMC Neuroscience 2021 22:14

  3. Nociceptin/orphanin FQ (N/OFQ) has been revealed to play bidirectional roles in orofacial pain modulation. Calcitonin gene-related peptide (CGRP) is a well-known pro-nociceptive molecule that participates in t...

    Authors: Xinyu Yan, Han Han, Shizhen Zhang, Yanzhu Lu, Linghuan Ren, Yufei Tang, Xiaolong Li, Fan Jian, Yan Wang, Hu Long and Wenli Lai

    Citation: BMC Neuroscience 2021 22:25

    Content type: Research article

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  4. Methamphetamine (METH) is one of the most widely abused illicit substances worldwide; unfortunately, its addiction mechanism remains unclear. Based on accumulating evidence, changes in gene expression and chro...

    Authors: Hui Li, Jing-An Chen, Qian-Zhi Ding, Guan-Yi Lu, Ning Wu, Rui-Bin Su, Fei Li and Jin Li

    Citation: BMC Neuroscience 2021 22:24

    Content type: Research article

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  5. Tau theory explains how both intrinsically and perceptually guided movements are controlled by the brain. According to general tau theory, voluntary, self-paced human movements are controlled by coupling the t...

    Authors: Mehrdad Bahadori, Paola Cesari, Cathy Craig and Mehran Emadi Andani

    Citation: BMC Neuroscience 2021 22:23

    Content type: Research article

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  6. Differences of genotypes between male and female have been studied in Parkinson’s disease (PD), but limited research has focused on the comparison between sexes with LRRK2 G2385 variant.

    Authors: Shi-Shuang Cui, Rao Fu, Juan-Juan Du, Yi-Qi Lin, Pei Huang, Chao Gao, Hai-Yan Zhou and Sheng-Di Chen

    Citation: BMC Neuroscience 2021 22:22

    Content type: Research article

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  7. Hepatic encephalopathy (HE) is a neurological complication resulting from acute or chronic liver disease. Hyperammonemia leading to astrocyte swelling and cerebral edema in combination with neuroinflammation i...

    Authors: Fatme Seval Ismail, Timo Jendrik Faustmann, Franco Corvace, Anamariya Tsvetanova, Zahra Moinfar and Pedro M. Faustmann

    Citation: BMC Neuroscience 2021 22:21

    Content type: Research article

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  8. Atherosclerotic plaques are often present in regions of arteries with complicated flow patterns. Vascular morphology plays important role in hemodynamics. In this study, we investigated the relationship betwee...

    Authors: Jinmei Zheng, Bin Sun, Ruolan Lin, Yongqi Teng, Xihai Zhao and Yunjing Xue

    Citation: BMC Neuroscience 2021 22:20

    Content type: Research article

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  9. The SCN11A gene, encoded Nav1.9 TTX resistant sodium channels, is a main effector in peripheral inflammation related pain in nociceptive neurons. The role of SCN11A gene in the auditory system has not been well c...

    Authors: Mian Zu, Wei-Wei Guo, Tao Cong, Fei Ji, Shi-Li Zhang, Yue Zhang, Xin Song, Wei Sun, David Z. Z. He, Wei-Guo Shi and Shi-Ming Yang

    Citation: BMC Neuroscience 2021 22:18

    Content type: Research article

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  10. Several studies have shown that glutamate neurotransmission in the nucleus accumbens (NAc) is required for the development of morphine-induced conditional place preference (CPP). In addition, metabotropic glut...

    Authors: Zahra Ebrahimi, Nazanin Kahvandi, Alireza Komaki, Seyed Asaad Karimi, Marzieh Naderishahab and Abdolrahman Sarihi

    Citation: BMC Neuroscience 2021 22:17

    Content type: Research article

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  11. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Laszlo Szpisjak, Gabor Szaraz, Andras Salamon, Viola L. Nemeth, Noemi Szepfalusi, Gabor Veres, Balint Kincses, Zoltan Maroti, Tibor Kalmar, Malgorzata Rydzanicz, Rafal Ploski, Peter Klivenyi and Denes Zadori

    Citation: BMC Neuroscience 2021 22:16

    Content type: Correction

    Published on:

    The original article was published in BMC Neuroscience 2021 22:7

  12. Rupture of intracranial aneurysm (IA) is the main cause of devastating subarachnoid hemorrhage, which urges our understanding of the pathogenesis and regulatory mechanisms of IA. However, the regulatory roles ...

    Authors: Yuan-Bo Pan, Jianan Lu, Biao Yang, Cameron Lenahan, Jianmin Zhang and Anwen Shao

    Citation: BMC Neuroscience 2021 22:15

    Content type: Research article

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  13. Alzheimer’s disease (AD) is characterized by cognitive impairment that eventually develops into dementia. Amyloid-beta (Aβ) accumulation is a widely described hallmark in AD, and has been reported to cause olf...

    Authors: Mara A. Guzmán-Ruiz, Amor Herrera-González, Adriana Jiménez, Alan Candelas-Juárez, Crystal Quiroga-Lozano, Claudia Castillo-Díaz, Erika Orta-Salazar, Diana Organista-Juárez, Sofía Díaz-Cintra and Rosalinda Guevara-Guzmán

    Citation: BMC Neuroscience 2021 22:14

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Neuroscience 2021 22:27

  14. Aside from the homeostatic and circadian components, light has itself an important, direct as well as indirect role in sleep regulation. Light exerts indirect sleep effect by modulating the circadian rhythms. ...

    Authors: Örs Szalontai, Attila Tóth, Máté Pethő, Dóra Keserű, Tünde Hajnik and László Détári

    Citation: BMC Neuroscience 2021 22:13

    Content type: Research article

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  15. Men and women show differences in sensitivity to reward and punishment, which may impact behavior in health and disease. However, the neural bases of these sex differences remain under-investigated. Here, by c...

    Authors: Isha Dhingra, Sheng Zhang, Simon Zhornitsky, Wuyi Wang, Thang M. Le and Chiang-Shan R. Li

    Citation: BMC Neuroscience 2021 22:12

    Content type: Research article

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  16. Attachment theory demonstrates that early attachment experience shapes internal working models with mental representations of self and close relationships, which affects personality traits and interpersonal re...

    Authors: Min Deng, Xing Zhang, Xiaoyan Bi and Chunhai Gao

    Citation: BMC Neuroscience 2021 22:11

    Content type: Research article

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  17. There is growing evidence for a positive correlation between measures of muscular strength and cognitive abilities. However, the neurophysiological correlates of this relationship are not well understood so fa...

    Authors: Fabian Herold, Tom Behrendt, Alexander Törpel, Dennis Hamacher, Notger G. Müller and Lutz Schega

    Citation: BMC Neuroscience 2021 22:10

    Content type: Research article

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  18. We previously reported that heat shock protein 27 (HSP27) phosphorylation plays an important role in the activation of glucose-6-phosphate dehydrogenase (G6PD), resulting in the upregulation of the pentose pho...

    Authors: Kazuya Matsuo, Kohkichi Hosoda, Jun Tanaka, Yusuke Yamamoto, Taichiro Imahori, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Takashi Sasayama and Eiji Kohmura

    Citation: BMC Neuroscience 2021 22:9

    Content type: Research article

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  19. It has been shown that eosinophils are decreased and monocytes are elevated in patients with acute ischemic stroke (AIS), but the impact of eosinophil-to-monocyte ratio (EMR) on clinical outcomes among AIS pat...

    Authors: Shuhong Yu, Yi Luo, Tan Zhang, Chenrong Huang, Yu Fu, Qiang Zhang, Fangyue Zeng, Hao Huang, Chunyuan Zhang and Zhiliang Guo

    Citation: BMC Neuroscience 2021 22:8

    Content type: Research article

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  20. SYNE1 ataxia is an autosomal recessive hereditary condition, the main characteristic features of which are gait and limb ataxia and cerebellar dysarthria. Reports have revealed that the clinical phenotype of SYNE...

    Authors: Laszlo Szpisjak, Gabor Szaraz, Andras Salamon, Viola L. Nemeth, Noemi Szepfalusi, Gabor Veres, Balint Kincses, Zoltan Maroti, Tibor Kalmar, Malgorzata Rydzanicz, Rafal Ploski, Peter Klivenyi and Denes Zadori

    Citation: BMC Neuroscience 2021 22:7

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Neuroscience 2021 22:16

  21. Neuropathic pain (NeuP) is a complex, debilitating condition of the somatosensory system, where dysregulation between pro- and anti-inflammatory cytokines and chemokines are believed to play a pivotal role. As...

    Authors: Mika Jönsson, Björn Gerdle, Bijar Ghafouri and Emmanuel Bäckryd

    Citation: BMC Neuroscience 2021 22:6

    Content type: Research article

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  22. The Period Circadian Regulator 2 (Per2) gene is important for the modulation of circadian rhythms that influence biological processes. Circadian control of the hypothalamus-pituitary-adrenal (HPA) axis is critica...

    Authors: Ashley L. Russell, Lauren Miller, Hannah Yi, Rita Keil, Robert J. Handa and T. John Wu

    Citation: BMC Neuroscience 2021 22:5

    Content type: Research article

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  23. Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflammatory cytokines released by activated microglia in various neurologic...

    Authors: Emilia Zgórzyńska, Dawid Stulczewski, Barbara Dziedzic, Kuan-Pin Su and Anna Walczewska

    Citation: BMC Neuroscience 2021 22:4

    Content type: Research article

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  24. Status epilepticus (SE) is a life-threatening neurological disorder. The hippocampus, as an important area of the brain that regulates cognitive function, is usually damaged after SE, and cognitive deficits of...

    Authors: Xin-Ming Luo, Jing Zhao, Wen-Yue Wu, Jie Fu, Zheng-Yu Li, Ming Zhang and Jie Lu

    Citation: BMC Neuroscience 2021 22:2

    Content type: Research article

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  25. A common problem in neurophysiological signal processing is the extraction of meaningful information from high dimension, low sample size data (HDLSS). We present RoLDSIS (regression on low-dimension spanned i...

    Authors: Adrielle C. Santana, Adriano V. Barbosa, Hani C. Yehia and Rafael Laboissière

    Citation: BMC Neuroscience 2021 22:1

    Content type: Methodology article

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  26. Conditioned pain modulation (CPM) evaluates the effect of a painful conditioning stimulus (CS) on a painful test stimulus (TS). Using painful cutaneous electrical stimulation (PCES) as TS and painful cold wate...

    Authors: A. T. L. Do, E. K. Enax-Krumova, Ö. Özgül, L. B. Eitner, S. Heba, M. Tegenthoff, C. Maier and O. Höffken

    Citation: BMC Neuroscience 2020 21:53

    Content type: Research article

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  27. Ventromedial hypothalamic nucleus (VMN) gluco-regulatory transmission is subject to sex-specific control by estradiol. The VMN is characterized by high levels of aromatase expression.

    Authors: Md. Main Uddin, Mostafa M. H. Ibrahim and Karen P. Briski

    Citation: BMC Neuroscience 2020 21:51

    Content type: Research article

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  28. Transcription factor 4 (TCF4) has been linked to human neurodevelopmental disorders such as intellectual disability, Pitt-Hopkins Syndrome (PTHS), autism, and schizophrenia. Recent work demonstrated that TCF4 par...

    Authors: Katharina Braun, Benjamin M. Häberle, Marie-Theres Wittmann and D. Chichung Lie

    Citation: BMC Neuroscience 2020 21:50

    Content type: Research article

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  29. Previous studies have demonstrated that individuals with autism spectrum disorder (ASD) exhibit dysfunction in the three attention systems (i.e., alerting, orienting, and executive control) as well as atypical re...

    Authors: Sayaka Yoshimura, Kei Kobayashi, Tsukasa Ueno, Takashi Miyagi, Naoya Oishi, Toshiya Murai and Hironobu Fujiwara

    Citation: BMC Neuroscience 2020 21:49

    Content type: Research article

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  30. To identify mechanisms of cortical plasticity of the visual cortex and to quantify their significance, sensitive parameters are warranted. In this context, multifocal visual evoked potentials (mfVEPs) can make...

    Authors: Robert Kolbe, Aykut Aytulun, Ann-Kristin Müller, Marius Ringelstein, Orhan Aktas, Alfons Schnitzler, Hans-Peter Hartung, Stefan Jun Groiss and Philipp Albrecht

    Citation: BMC Neuroscience 2020 21:48

    Content type: Research article

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  31. We present first-time evidence for the immediate neural and behavioral effects of bifocal emotional processing via visualized tapping for two different types of negative emotions (fear and disgust) in a sample...

    Authors: Dina Wittfoth, Antonia Pfeiffer, Michael Bohne, Heinrich Lanfermann and Matthias Wittfoth

    Citation: BMC Neuroscience 2020 21:47

    Content type: Research article

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  32. As a noninvasive perfusion-weighted MRI technique, arterial spin-labeling (ASL) was becoming increasingly used to evaluate cerebral hemodynamics in many studies. The relation between ASL-MRI and crossed cerebe...

    Authors: Juan Wang, Li-Jun Pan, Bin Zhou, Jin-Yan Zu, Yi-Xu Zhao, Yang Li, Wan-Qiu Zhu, Lei Li, Jian-Rong Xu and Zeng-Ai Chen

    Citation: BMC Neuroscience 2020 21:46

    Content type: Research article

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  33. Cardiac arrest (CA) is the most common cause of acute neurologic insult in children. Many survivors have significant neurocognitive deficits at 1 year of recovery. Epoxyeicosatrienoic acids (EETs) are multifun...

    Authors: Caitlin E. O’Brien, Polan T. Santos, Ewa Kulikowicz, Jennifer K. Lee, Raymond C. Koehler and Lee J. Martin

    Citation: BMC Neuroscience 2020 21:43

    Content type: Research article

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  34. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative fatal disease that can affect the neurons of brain and spinal cord. ALS genetics has identified various genes to be associated with diseas...

    Authors: Surinder Pal, Abha Tiwari, Kaushal Sharma and Suresh Kumar Sharma

    Citation: BMC Neuroscience 2020 21:42

    Content type: Research article

    Published on:

  35. During voluntary muscle contraction, sensory information induced by electrostimulation of the nerves supplying the contracting muscle is inhibited and the somatosensory evoked potentials (SEPs) amplitude decre...

    Authors: Terumasa Takahara, Hidetaka Yamaguchi, Kazutoshi Seki and Sho Onodera

    Citation: BMC Neuroscience 2020 21:41

    Content type: Research article

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  36. Serotonin is a neurotransmitter that has been linked to a wide variety of behaviors including feeding and body-weight regulation, social hierarchies, aggression and suicidality, obsessive compulsive disorder, ...

    Authors: Janet Best, William Duncan, Farrah Sadre-Marandi, Parastoo Hashemi, H. Frederik Nijhout and Michael Reed

    Citation: BMC Neuroscience 2020 21:40

    Content type: Research article

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  37. ADHD is one of the most common psychiatric disorders in children and adolescents. Altered functional connectivity has been associated with ADHD symptoms. This study aimed to investigate abnormal changes in the...

    Authors: Huayu Zhang, Yue Zhao, Weifang Cao, Dong Cui, Qing Jiao, Weizhao Lu, Hongyu Li and Jianfeng Qiu

    Citation: BMC Neuroscience 2020 21:39

    Content type: Research article

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  38. Glucose fluctuation promotes neuronal apoptosis, which plays a central role in diabetic encephalopathy (DE). Nerve growth factor (NGF), and its interaction with high-affinity (TrkA) and low-affinity (p75NTR) r...

    Authors: Ting Yan, Zhihui Zhang and Danqing Li

    Citation: BMC Neuroscience 2020 21:38

    Content type: Research article

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  39. Although previous studies have shown that intra-network abnormalities in brain functional networks are correlated with clinical/cognitive impairment in multiple sclerosis (MS), there is little information rega...

    Authors: Lin Wu, Muhua Huang, Fuqing Zhou, Xianjun Zeng and Honghan Gong

    Citation: BMC Neuroscience 2020 21:37

    Content type: Research article

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  40. Frontotemporal dementia (FTD) is the second leading cause of early onset dementia following Alzheimer’s disease. It involves atrophy of the frontal and temporal regions of the brain affecting language, memory,...

    Authors: Lalitha Venkataraman, Ping He, Galam Khan, Brent T. Harris and Michael R. Sierks

    Citation: BMC Neuroscience 2020 21:36

    Content type: Research article

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  41. The inter-scanner reproducibility of brain volumetry is important in multi-site neuroimaging studies, where the reliability of automated brain segmentation (ABS) tools plays an important role. This study aimed...

    Authors: Sirui Liu, Bo Hou, Yiwei Zhang, Tianye Lin, Xiaoyuan Fan, Hui You and Feng Feng

    Citation: BMC Neuroscience 2020 21:35

    Content type: Research article

    Published on:

  42. When planning nerve conduction studies using animal models, the sciatic nerve is often used and the upper extremity nerves are not preferred due to the size of laboratory animals. This study aimed to present t...

    Authors: Basak Mansiz-Kaplan, Secil Pervane-Vural, Koray Gursoy and Baris Nacir

    Citation: BMC Neuroscience 2020 21:34

    Content type: Methodology article

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  43. Alzheimer’s disease (AD) is a progressive neuro-degenerative disease with a major manifestation of dementia. MicroRNAs were reported to regulate the transcript expression in patients with Alzheimer’s disease (...

    Authors: Jin Miao, Jin Jing, Yixiang Shao and Huaichang Sun

    Citation: BMC Neuroscience 2020 21:33

    Content type: Research article

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