Figure 4

NMDA receptor-independent LTP is unimpaired in Kal7^KO animals. A) Example traces of evoked fEPSPS before (black) and 60 min after (red) LTP induction (200 Hz/2 sec in the presence of 3 μM CPP). Calibration bars: 0.1 mV, 20 ms. B) Representative examples from a WT and a Kal7^KO animal showing initial depression and slowly developing potentiation. LTP induction occurred at time zero. B) Group data showing the magnitude of NMDA receptor-independent LTP in WT and Kal7^KO animals 60 min post-induction (n = 7-8 animals, 2 slices/animal). *, p < 0.05 compared to baseline; ns, no significant difference between genotypes.