Targeting choroid plexus epithelia and ventricular ependyma for drug delivery to the central nervous system

BMC Neuroscience

Table 1 Identification of CP-targeting peptides.

Clone	Sequence	Family	Repeat	Clone	Sequence	Family	Repeat
3.1	CHERPSSLC	3		4.2	CKALDATTC	4
3.2	CPAVVRGSC	5		4.5	CSASTHKAC	4
3.3	CDHRSSAQC	3		4.7	CTSTSYKMC	5	3.6/4.15
3.5	CLRSQGPVC	1		4.8	CTKMHLPQC	6
3.6	CTSTSYKMC	4	4.7	4.11	CAPHSTSAC	5
3.7	CQPTHSQSC	2		4.12	CHHPQNRHC	6
3.8	CSMPHLTSC	5		4.15	CSASTHKAC	4	3.18/4.5
3.9	CHGNHMPAC	1	3.23/3.24	4.16	CHGPIDKSC	6
3.10	CKSIPTNAC	4		4.19	CIPTSIRHC	5
3.12	CMSGKHLKC	4		4.23	CSPKGSHSC	5
3.15	CLRDDSHSC	1
3.16	CHHQHSPQC	1
3.17	CEWPTSSTC	3
3.18	CSASTHKAC	4	4.15
3.19	CNSHASPHC	1
3.21	CIIGQGPSC	1
3.22	CMMPSRSLC	5
3.23	CHGNHMPAC	1	3.24/3.9
3.24	CHGNHMPAC	1	3.23/3.9

Peptide sequences obtained from after 3 and 4 rounds of biopanning were compared, assigned to one of six different families of sequences and repeat recoveries noted as described in the text.

ISSN: 1471-2202