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Figure 9 | BMC Neuroscience

Figure 9

From: Dexamethasone inhibits the Nox-dependent ROS production via suppression of MKP-1-dependent MAPK pathways in activated microglia

Figure 9

A-H. Confocal images showing the MKP-1 expression (red) in lectin-positive (green) microglia in corpus callosum of 3 day postnatal and in OX42 postive (green) microglia in the corpus callosum of 4 week old rat brain subjected to different treatments. MKP-1 immunoreactivity is hardly detectable in microglia of control rats injected with saline (A, E) and with Dex alone (B,F). MKP-1 immunoreactivity appears to be upregulated in microglia distributed in the corpus callosum region of rats that received LPS (C, G) or LPS and Dex (D, H).Scale bar (A-D), 50 μm; Scale bar (E-H), 20 μm.

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BMC Neuroscience

ISSN: 1471-2202

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