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Table 3 Brain regions showing significant correlations with clinical scores

From: Lateral frontal cortex volume reduction in Tourette syndrome revealed by VBM

Anatomical area

L/R

Cluster size

T-value

x

y

z

GM correlations with RVTRS

      

Premotor cortex

R

157

4.58

16

6

55

Insula

L

255

4.41

-31

6

4

Precuneus

R

185

4.07

3

-57

31

Posterior cingulate cortex

R

101

4.02

10

-40

25

IFG

R

96

3.87

30

28

-4

GM correlations with Y-BOCS (total score)

      

Postcentral gyrus

L

374

5.75

-38

-39

60

Superior parietal lobule

R

184

4.96

15

-67

52

Occipital pole

R

449

4.34

22

-100

9

GM correlations with ADHD scores (Symptom checklist, CAARS, WURS-K)

      

Putamen

L

433

4.73

-26

9

-9

 

R

503

4.94

20

6

-12

GM correlations with BDI

      

Anterior cingulate cortex

L

202

4.44

2

14

18

Middle temporal gyrus

L

90

4.34

-51

-49

-2

Lateral occipitotemporal gyrus

R

90

4.30

39

-48

-17

GM correlations with STAI

      

Anterior cingulate cortex

L

1423

5.07

-16

47

7

Insula

R

383

5.01

48

-3

1

 

L

558

4.91

-42

9

-3

Middle occipital gyrus

L

135

4.60

-39

-61

24

Lateral occipitotemporal gyrus

R

105

4.47

36

-52

-8

Midcingulate cortex

L

149

4.35

-3

-27

40

Middle frontal gyrus

R

158

4.19

26

58

1

 

L

141

4.14

-30

60

1

Superior parietal lobule

R

278

4.12

0

-64

46

Medial frontal gyrus

L

132

3.91

-6

35

42