Table 2 Functional Activations for High-Calorie, Low-Calorie and Non-Food Object Contrasts at Baseline in Obese Endometrial Cancer Patients Enrolled in a 16-Session Group Behavioral Lifestyle Intervention
|  |   Brain Region (Hemisphere) | Pre-Meal (Fasted) | Post-Meal (Fed/Satiated) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Peak Voxel | Peak Voxel | ||||||||||
x | y | z | Cluster Size* | t | x | y | z | Cluster Size* | t | ||
↑ Activation | High Calorie vs. Low Calorie Food | ||||||||||
   Insula (BA = 13) |  |  |  |  |  | 44 | -11 | 18 | 524 | 5.67 | |
   Cingulate Gyrus (BA = 31) |  |  |  |  |  | 22 | -21 | 44 | 491 | 6.04 | |
   Precentral Gyrus (BA = 4) |  |  |  |  |  | 53 | -4 | 15 | 422 | 5.49 | |
High Calorie vs. Non-Food Object | |||||||||||
   OFC (Bilateral; BA = 47) | -47 | 32 | -7 | 839 | 14.5 |  |  |  |  |  | |
   Medial Frontal Gyrus (BA = 6) | -9 | 28 | 37 | 897 | 11.6 |  |  |  |  |  | |
   Anterior PFC (BA = 10) | -8 | 56 | 19 | 825 | 10.4 |  |  |  |  |  | |
   Dorsolateral PFC (BA = 9) | -42 | 3 | 28 | 994 | 10.4 |  |  |  |  |  | |
   Dorsolateral PFC (BA = 46) | 45 | 32 | 11 | 937 | 7.93 |  |  |  |  |  | |
   Middle Frontal Gyrus (BA = 8) | -39 | 26 | 42 | 648 | 8.27 |  |  |  |  |  | |
   Thalamus (Bilateral) |  |  |  |  |  | 9 | -16 | 3 | 847 | 5.00 | |
   Posterior Cingulate (BA = 29) |  |  |  |  |  | -7 | -45 | 18 | 491 | 5.24 | |
   Precuneus (BA = 7) |  |  |  |  |  | -24 | -77 | 47 | 535 | 7.65 | |
Low Calorie vs. Non-Food Object | |||||||||||
   Putamen | -24 | 0 | 16 | 756 | 9.35 |  |  |  |  |  | |
   Claustrum | 24 | 12 | 15 | 830 | 9.89 |  |  |  |  |  | |
   Caudate | -8 | 7 | 14 | 783 | 7.64 |  |  |  |  |  | |
   Caudate | 13 | -2 | 17 | 296 | 5.17 |  |  |  |  |  | |
   Anterior PFC (BA = 10) | -32 | 64 | 4 | 635 | 8.70 |  |  |  |  |  | |
   Superior Frontal Gyrus (BA = 8) | -22 | 19 | 46 | 517 | 8.03 |  |  |  |  |  | |
↓ Activation | High Calorie vs. Low Calorie Food | ||||||||||
   Anterior Cingulate | 21 | 39 | 15 | 766 | -10.9 |  |  |  |  |  | |
High Calorie vs. Non-Food Object | |||||||||||
   No regions survived threshold |  |  |  |  |  |  |  |  |  |  | |
Low Calorie vs. Non-Food Object | |||||||||||
|  |    Culmen |  |  |  |  |  | 22 | -47 | -12 | 639 | -6.72 |