Figure 3

Conservation of LOC689986 orthologs in the vertebrate lineage. A. Analysis of the sequence conservation of LOC689986 in various vertebrate species, generated by the UCSC browser (http://genome.ucsc.edu/). B. Illustration of the genetic synteny in various vertebrate species, generated by the Genomicus v64.01 database. The human orthologous gene (C1orf146) was used as a reference gene. The orthologous genes from various vertebrates are illustrated as a light green box in the centre of the image (indicated by an arrow). The surrounding genes that are in common between the vertebrate species are illustrated by coloured boxes (ranging from red to purple from left to right, respectively). Shaded boxes illustrate genes that are not derived from the same ancestral genomic region. The species names are listed to the right. A phylogenetic tree illustrating the evolutionary relationship between the various vertebrate species was also generated by the Genomicus v64.01 database (shown to the left). Blue squares represent speciation nodes, while the red square represents a duplication node.