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Figure 8 | BMC Neuroscience

Figure 8

From: Hirano bodies differentially modulate cell death induced by tau and the amyloid precursor protein intracellular domain

Figure 8

Immunohistochemistry localization of tau and Hirano bodies in human brains. Immunohistochemistry was performed on paraffin embedded human brain sections using Tau5 or pTau-199/202 antibodies following an eosin counterstain to visualize Hirano bodies (arrows). Tau5 antibodies colocalized with Hirano bodies in both Alzheimer diseased and control brains while pTau-199/202 colocalized with Hirano bodies only in Alzheimer diseased brains. Scale bar = 50 μm

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BMC Neuroscience

ISSN: 1471-2202

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