Figure 4From: Lithium enhances survival and regrowth of spinal motoneurons after ventral root avulsionThe effects of ventral root reimplantation and lithium on the axonal regeneration in the median nerves at 40 mm distal to the reimplantation site at 20 weeks post-reimplantation. Figures 4A-E and a-e: A large of number of myelinated axons were present in the normal median nerve (A-a). However, the decreased presence of nerve fibers and obvious nerve atrophy were observed in both the Av + PBS (B-b) and Av + Li (C-c) subgroups. In both the Re + PBS (D-d) and Re + Li (E-e) subgroups, a small amount of uneven size nerve fibers re-appeared and were scattered in location. Scale bar = 100 μm. Figures 4F-J: The frequency distribution of myelinated fiber diameters in the normal control (F), Av + PBS (G), Av + Li (H), Re + PBS (I) and Re + Li (J) subgroups were estimated. Figures 4K-L: The results of statistical analysis of the mean number (4K) and diameter (4L) of the median nerve were summarized. The results showed that the Av + PBS subgroup showed the lowest values and the Re + Li subgroup showed the highest values among the treated subgroups. *p < 0.05 compared to the normal subgroup, #p < 0.05 compared to the Av + PBS subgroup, ^p < 0.05 compared to the Av + Li subgroup, and △p < 0.05 compared to the Re + PBS subgroup.Back to article page