Human area MT+shows load-dependent activation during working memory maintenance with continuously morphing stimulation

Table 1 Fronto-parietal network consistently involved in WM maintenance under higher memory load conditions

Anatomical region (BA, r)	Side	Cluster size (voxels)	t-value	Peak coordinate
				x	y	z
Superior parietal lobule (BA 7, r = 5)	R	4899	11.59	18	−65	55
Superior parietal lobule (BA 7, r = 3)			9.75	26	−58	53
Inferior parietal lobule (BA 40, r = 5)			9.72	40	−33	46
Inferior parietal lobule (BA 40)	L	5585	9.70	−36	−44	48
Precuneus (BA 7, r = 3)			9.22	−18	−69	51
Middle occipital gyrus (BA19)			9.21	−46	−74	−5
Middle frontal gyrus (BA 6, r = 3)	L	1146	9.69	−28	−1	55
Inferior frontal gyrus (BA 9)			6.05	−57	9	27
Inferior frontal gyrus (BA 9, r = 5)			6.02	−50	9	24
Middle frontal gyrus (BA 6, r = 3)	R	827	9.61	30	1	57
Inferior frontal gyrus (BA 47, r = 5)	L	155	6.56	−32	21	−3
Medial frontal gyrus (BA 6, r = 3 /BA32)	L	330	6.47	−4	14	47
Medial frontal gyrus (BA 6)			6.19	6	16	45
Inferior frontal gyrus (BA 47, r = 7)	R	109	6.36	32	25	−5
Lentiform nucleus	L	39	5.29	−12	2	0
Middle frontal gyrus (BA 8, r = 3)	R	54	4.93	48	8	42
Middle frontal gyrus (BA 6, r = 3)			4.78	42	4	38
Cerebellum culmen	R	22	4.92	36	−53	−21
Caudate head (r = 3)	R	33	4.87	12	8	1
Inferior frontal gyrus (BA 44, r = 5)	R	42	4.77	50	11	22
Inferior frontal gyrus (BA 44, r = 3)			4.40	51	12	12
Inferior frontal gyrus (BA 45, r = 5)			4.24	57	15	21
Cerebellum declive	R	49	4.67	28	−75	−16

Talairach coordinates of activation peaks revealed by a conjunction analysis of the maintenance period of complex trials versus maintenance period of simple trials conjunct over all four delay durations (FDR-corrected, p < .001; k > 20). Anatomical labels of peak activations are listed in boldface and significant sub-peaks are listed without boldface. Abbreviations: BA = Brodmann area; r = range of nearest gray matter in mm; R = right hemisphere; L = left hemisphere.

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