Table 3 Lamina cribrosa cell and ONH astrocyte responses to recovery following oxygen-glucose deprivation.
| Â | Lamina cribrosa cells | ONH astrocytes |
|---|---|---|
Cell Number | 80 % survival | 80 % survival |
NT Expression | ↑ BDNF; others near control levels | ↑ NGF |
Trk Expression | ↓ Trk A, ↓ Trk C | ↑ Trk A |
Phospho-Trk Expression | ↓ 148 kDa isoform; others near control levels | ↑ 120 kDa isoform (Trk A); ↓ 148 kDa isoform |
Secretion of NTs | near control levels | ↓ BDNF |