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Figure 2 | BMC Neuroscience

Figure 2

From: Adrenalectomy promotes a permanent decrease of plasma corticoid levels and a transient increase of apoptosis and the expression of Transforming Growth Factor β1 (TGF-β1) in hippocampus: effect of a TGF-β1 oligo-antisense

Figure 2

ADX increased TGF-β1 NA expression in the hippocampus. Photomicrographs show the changes in TGF-β1 mRNA levels in hippocampus of: (A) control (sham-operated), (B) 2 days after ADX (ADX-2), and (C) 5 days after ADX (ADX-5) animals. The in situ hybridisation was performed using a digoxigenin-labelled oligonucleotide probe complementary to TGF-β1 mRNA (524 pb – 563 bp; accession number NM_021578.1). The specificity of the hybridisation was evaluated using a 100-fold excess of unlabelled oligonucleotide (D). Scale bar = 500 μm.

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