Figure 4From: Neural stem cells from protein tyrosine phosphatase sigma knockout mice generate an altered neuronal phenotype in cultureNeurite length of differentiated neurons (identified by b-III tubulin immunocytochemistry) grown on laminin coated glass coverslips. The data (average of all neurites ±SEM) show a significant increase in neurite outgrowth from the PTPs(-/-) mice (KO) relative to sibling (Sib) controls. Data represent 4 separate experiments with a total of 469 neurites measured for the knockout mice and 573 neurites for the siblings. KO represents mice genotyped as PTPs (-/-) and Sib represents mice genotyped as PTPs(+/-) or PTPs (+/+). There was no difference in the length of neurites between the neurons from the PTPs(+/+) or (+/-) neurospheres, hence their data were combined.Back to article page