Fig. 4
From: High-fat diet-induced obesity exacerbates kainic acid-induced hippocampal cell death
Effects of a HFD on KA-induced neuroinflammation. Western blot analysis of HMGB1 (a) and TRL4 (b). Densitometry values for each protein were normalized to β-actin and expressed as fold change relative to the ND group. c Representative immunofluorescence images of iba-1 in the CA3 region after KA treatment. Scale bar 50 µm. a ND; b ND + KA; c HFD; d HFD + KA. d Western blot analysis of hippocampal iba-1 levels after KA treatment. Densitometry values for iba-1 were normalized to β-actin and expressed as fold change relative to the ND group. Data are shown as mean ± SEM (n = 4 mice per group). *p < 0.05 versus ND. # p < 0.05 versus HFD. † p < 0.05 versus ND + KA