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Fig. 3 | BMC Neuroscience

Fig. 3

From: TNFAIP1 contributes to the neurotoxicity induced by Aβ25–35 in Neuro2a cells

Fig. 3

Effect of TNFAIP1 on Aβ25–35-induced the cleavage of caspase-3. a Cleaved caspase-3 protein levels were measured by Western blot in N2a cells cultured in 6 wells plate and transfected with 50 pmol of Control siRNA or TNFAIP1 siRNA, followed by treated by Aβ25–35 (20 μM). b Quantitative analysis of Cleaved caspase-3 protein levels (fold of control) in N2a cells. Data are expressed as mean ± SD, n = 3, *p < 0.05 compared with Control siRNA, #p < 0.05 compared with Control siRNA plus Aβ25–35 (20 μM). c Cleaved caspase-3 protein levels were measured by Western blot in N2a cells cultured in 6 wells plate and transfected with 4 μg of pCMV-Myc or Myc-TNFAIP1, followed by treated by Aβ25–35 (20 μM). d Quantitative analysis of Cleaved caspase-3 protein levels (fold of control) in N2a cells. Data are expressed as mean ± SD, n = 3, *p < 0.05, **p < 0.01 compared with pCMV-Myc

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