Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides

Table 4 Timing for recovery of evocable CMAPs

Muscle	Nerve guide	60 days		90 days		120 days		150 days
Muscle	Nerve guide	Animals/group	[%]	Animals/group	[%]	Animals/group	[%]	Animals/group	[%]
Tibialis anterior	hCNG-II	1/10	10*	4/10	40	5/10	50	5/10	50
Tibialis anterior	CFeCNG-II	0/7	0	1/7	14	3/7	43	5/7	71*
Plantar interosseus	hCNG-II	0/10	0	0/10	0	1/10	10*	1/10	10*
Plantar interosseus	CFeCNG-II	0/7	0	0/7	0	0/7	0	0/7	0

The table gives a timeline of functional motor recovery detected as evocable CMAPs recorded from the tibialis anterior or plantar muscles upon transcutaneous stimulation of the reconstructed sciatic nerve. * Indicates a significant difference (p < 0.05) between hCNG-II and CFeCNG-II at the same time point and for the same muscle as determined in the Chi square test

ISSN: 1471-2202