Fig. 4

Effects of mul1 and park mutations on ATG5 expression level in clock neurons and the Drosophila brain. a–c Co-localization of ATG5 and PDF in cell bodies of large ventral lateral clock neurons in w¹¹¹⁸ (a), park¹ (b) and mul1^A6 (c). Scale bar: 50 µm. d ATG5 level in the l-LNvs (four asterisks indicate p < 0.01) (means ± SD). N of w¹¹¹⁸ = 23, N of park¹ = 21, N of mul1^A6 = 15. e ATG5 in the whole Drosophila brain (means ± SD). Statistically significant differences were found between all genotypes studied (one asterisk indicates p < 0.05; three asterisks indicate p < 0.01). N of w¹¹¹⁸ = 90, N of park¹ = 90, N of mul1^A6 = 90