Fig. 6

Time–frequency relationship among trisynaptic circuit regions at a fast ripple event. a Raw intracranial EEG recordings in each trisynaptic circuit region. Arrow is pointing to the maximum peak-to-peak amplitude of the fast ripple event recorded in CA1. b Wavelet coherence of the theta band (3–7 Hz) and gamma band (30–90 Hz) between regions. Note that the fast ripple is centered when theta coherence among all regions is increased. c Statistical comparison of the mean coherence amplitude among the trisynaptic regions 200 ms before and after the maximum fast ripple peak-to-peak amplitude in the theta band (3–7 Hz) and gamma band (30–90 Hz). Calibration bar: 500 μV. The paired Wilcoxon test per connection was used (*p < .05, **p < .01, ***p < .001, ****p < .0001)