In vivo oxygen measurement in cerebrospinal fluid of pigs to determine physiologic and pathophysiologic oxygen values during CNS infections

Table 2 Scoring of histological findings of pigs uninfected and infected with S. suis serotype 2

Age of infected pigs (wk)	Total no. of pigs	Sex (f/m)	S. suis strain	No. of pigs/Total no. of pigs												ɷ^e
				Brain			Serosa			Spleen and liver			Lung
				Meningitis, choroiditis			Pleuritis or peritonitis			Splenitis^a or hepatitis			Pneumonia
				5^b	3^c	1^d	4^b	2^c	1^d	4^b	2^c	1^d	4^b	2^c	1^d
7–8	6	(3/3)	Uninfected	0/6	0/6	0/6	1/6	0/6	0/6	0/6	0/6	0/6	1/6	0/6	0/6	0.66
7–8	6	(1/5)	10	1/6	1/6*	0/6	0/6	0/6	0/6	0/6	2/6	0/6	1/6	0/6	0/6	1.17

*Minimally focal/multifocal lymphoplasmacellular Plexus chorioiditis (not in score)
^aNeutrophilic accumulation in the splenic red pulp
^bScoring of 4 and 5 indicates moderate to severe diffuse or multifocal fibrinosuppurative inflammations
^cScoring of 2 and 3 indicates mild focal fibrinosuppurative inflammation
^dIndividual single perivascular neutrophils received a score of 1
^eω = ∑score_max / n_animals[50]
wk = weeks; f = female; m = male

ISSN: 1471-2202