Table 3 Findings according to the age of DM1 patients
Age-group A ≤ 39 years old (n = 36) | Age-group B 40–49 years old (n = 42) | Age-group C ≥ 50 years old (n = 34) | Age-group A vs B | Age-group A vs C | Age-group B vs C | ||
|---|---|---|---|---|---|---|---|
Clinical characteristics | Age, mean (IQR) | 33.5 (29.5–36) | 45 (42–47) | 55.5 (53–61) | NA | NA | NA |
Sex, female (%) | 16 (44) | 15 (36) | 17 (50) | NS | NS | NS | |
DM related factors | CTG repeat numbers, mean (IQR) | 1100 (600–1450) | 950 (700–1200) | 833 (550–1200) | NS | NS | NS |
Imaging characteristics | z-Evans Index, mean (IQR) | 0.282 (0.250–0.303) | 0.291 (0.278–0.313) | 0.313 (0.283–0.374) | NS | * | ** |
Callosal angle, mean (IQR) | 123 (119–129) | 123 (112–129) | 125 (103–129) | NS | NS | NS | |
DESH, n (%) | 0 (0) | 2 (5) | 7 (21) | NS | * | NS | |
CS-EPVS, n (%) | 17 (47) | 10 (24) | 8 (24) | NS | NS | NS | |
Temporo-polar WML, n (%) | 25 (69) | 30 (71) | 27 (79) | NS | NS | NS | |
Pathological brain atrophy, n (%) | 13 (36) | 21 (50) | 12 (35) | NS | NS | NS |