Cascade process mediated by left hippocampus and left superior frontal gyrus affects relationship between aging and cognitive dysfunction

Table 1 Results of region volume

	Younger group		Elderly group
	Average	S.D	Average	S.D	p value
Left opercular part of inferior frontal gyrus	3072	437	2946	281	0.291
Left orbital part of inferior frontal gyrus	1065	152	1028	176	0.486
Left triangular part of inferior frontal gyrus	2426	481	2217	297	0.020
Left middle frontal gyrus	9904	1076	8706	1153	0.002
Left superior frontal gyrus	17,101	1289	15,377	1401	< 0.0001
Left hippocampus	4061	287	3555	306	< 0.0001
Right opercular part of inferior frontal gyrus	3268	438	2939	442	0.025
Right orbital part of inferior frontal gyrus	986	171	912	208	0.176
Right triangular part of inferior frontal gyrus	2114	394	1980	423	0.314
Right middle frontal gyrus	8758	1026	7818	802	0.003
Right superior frontal gyrus	16,116	1431	14,202	1399	< 0.0001
Right hippocampus	4276	344	3727	325	< 0.0001

MoCA Montreal Cognitive Assessment, Years of Education Years of education since entering elementary school
The standard deviations are shown in parentheses
The unit of region volume corrected by ICV is mm³
Unpaired t test was used to group comparison

ISSN: 1471-2202