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Fig. 1 | BMC Neuroscience

Fig. 1

From: Metformin attenuates sepsis-induced neuronal injury and cognitive impairment

Fig. 1

Cecum ligation and puncture triggers cognitive deficits in rats. A Experimental design sketch. The open field test results showed the total distance covered (B) and zone crossing (C). Novel object recognition test showed the time spent exploringthe new object at 2 hours (D) and 24 h (E). Morris water maze showed the latency to find the hidden platform (F). On day 6, with the platform removed, the time in the target quadrant (G), the number of target platform crossing (H) and swimming speed were analyzed (I). n  = 10. p value significance is calculated from T test, and data are represented as mean  ±  SEM. *p  < 0.05, **p  < 0.01 vs control group

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