Integrin β3 in forebrain Emx1-expressing cells regulates repetitive self-grooming and sociability in mice

BMC Neuroscience

Table 2 EPM, OFT, and MBT

	Experiment: Fig. 2A. EPM open arm entries					Experiment: Fig. 2B. EPM percent time in open arm
	Factor	DFn	DFd	F	p	Factor	DFn	DFd	F	p
Two-way ANOVA	Genotype	2	33	0.09343	0.9110	Genotype	2	33	0.1993	0.8203
	Sex	1	33	1.178	0.2857	Sex	1	33	0.8636	0.3595
	Interaction	2	33	0.07359	0.9292	Interaction	2	33	0.006488	0.9935

	Experiment: Fig. 2C. EPM duration of peeking behaviors (s)					Experiment: Fig. 2D. EPM number of peeking behaviors
	Factor	DFn	DFd	F	p	Factor	DFn	DFd	F	p
Two-way ANOVA	Genotype	2	33	1.384	0.2647	Genotype	2	33	0.3888	0.6810
	Sex	1	33	1.627	0.2110	Sex	1	33	0.03200	0.8591
	Interaction	2	33	0.2435	0.7853	Interaction	2	33	0.09161	0.9127

	Experiment: Fig. 2E. OFT distance traveled (m) per minute					Experiment: Fig. 2F. OFT number of crossings
	Factor	DFn	DFd	F	p	Factor	DFn	DFd	F	p
Two-way ANOVA	Genotype	2	33	0.4342	0.6516	Genotype	2	33	1.319	0.2815
	Sex	1	33	2.333	0.1365	Sex	1	33	0.1444	0.7064
	Interaction	2	33	0.2352	0.7918	Interaction	2	33	1.172	0.3227

	Experiment: Fig. 2G. Marble burying score
	Factor	DFn	DFd	F	p
Two-way ANOVA	Genotype	2	33	0.1674	0.8466
	Sex	1	33	1.688	0.2029
	Interaction	2	33	0.003392	0.9966

	Genotype: WT			Genotype: cHET			Genotype: cKO
	Experiment	n	Mean ± SEM	Experiment	n	Mean ± SEM	Experiment	n	Mean ± SEM
N, mean, SEM	Fig. 2A. EPM Open Arm Entries	18	9.47 ± 1.13	Fig. 2A. EPM Open Arm Entries	12	10.42 ± 1.63	Fig. 2A. EPM Open Arm Entries	9	9.11 ± 1.67
	Fig. 2B. EPM Percent Time in Open Arms	18	30.41 ± 3.88	Fig. 2B. EPM Percent Time in Open Arms	12	35.55 ± 4.95	Fig. 2B. EPM Percent Time in Open Arms	9	31.98 ± 4.61
	Fig. 2C. EPM Duration of Peeking Behaviors (s)	18	76.28 ± 5.67	Fig. 2C. EPM Duration of Peeking Behaviors (s)	12	61.50 ± 8.11	Fig. 2C. EPM Duration of Peeking Behaviors (s)	9	59.22 ± 7.91
	Fig. 2D. EPM Number of Peeking Behaviors	18	20.33 ± 1.19	Fig. 2D. EPM Number of Peeking Behaviors	12	20.67 ± 1.68	Fig. 2D. EPM Number of Peeking Behaviors	9	18.67 ± 2.16
	Fig. 2E. OFT Distance Traveled (m) per Minute	18	4.05 ± 0.25	Fig. 2E. OFT Distance Traveled (m) per Minute	12	4.59 ± 0.50	Fig. 2E. OFT Distance Traveled (m) per Minute	9	4.72 ± 0.74
	Fig. 2F. OFT Number of Crossings	18	17.06 ± 1.72	Fig. 2F. OFT Number of Crossings	12	25.36 ± 4.73	Fig. 2F. OFT Number of Crossings	9	19.22 ± 4.61
	Fig. 2G. Marble Burying Score	18	12.61 ± 2.30	Fig. 2G. Marble Burying Score	12	10.42 ± 2.07	Fig. 2G. Marble Burying Score	9	10.33 ± 2.22

Two-way ANOVA analyses of genotype (WT, cHET, cKO) and sex (female, male) factors in EPM, OFT, and MBT behaviors. See Additional file 2: Table S2 for within-group ANOVA comparisons and within-group N, Mean ± SEM

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