Frontal cortex | Glu-TRH | Peak 2 | TRH | Val-TRH | Tyr-TRH | Leu-TRH | Phe-TRH | Trp-TRH |
---|---|---|---|---|---|---|---|---|
CON | 80 ± 16 | 815 ± 156 | 1954 ± 207 | 1496 ± 307 | 3556 ± 580 | 1857 ± 696 | 1924 ± 327 | 736 ± 161 |
AC | 494 ± 101** | 945 ± 180 | 1598 ± 169 | 876 ± 180 | 1577 ± 257* | 868 ± 326 | 1132 ± 192 | 521 ± 114 |
CHR | 188 ± 39 | 1143 ± 218 | 1867 ± 198 | 1485 ± 304 | 4283 ± 698 | 1761 ± 660 | 1487 ± 253 | 837 ± 183 |
WD | 395 ± 81* | 874 ± 167 | 1310 ± 139 | 285 ± 59* | 1515 ± 247* | 904 ± 339 | 1087 ± 185 | 369 ± 81 |
Hypothalamus | ||||||||
CON | 657 ± 217 | 1771 ± 638 | 38,509 ± 12,323 | 0 | 0 | 1706 ± 699 | 999 ± 430 | 616 ± 172 |
AC | 638 ± 211 | 1690 ± 608 | 34,863 ± 11,156 | 0 | 0 | 1368 ± 561 | 1138 ± 489 | 436 ± 122 |
CHR | 644 ± 213 | 1914 ± 689 | 41,487 ± 13,276 | 0 | 0 | 1811 ± 743 | 943 ± 405 | 371 ± 104 |
WD | 841 ± 278 | 3983 ± 1434 | 28,634 ± 9163 | 0 | 0 | 1549 ± 635 | 1104 ± 475 | 915 ± 256 |
Amygdala | ||||||||
CON | 597 ± 169 | 1347 ± 180 | 513 ± 23 | 1312 ± 125 | 1543 ± 262 | 8408 ± 2262 | 1591 ± 248 | 1344 ± 285 |
AC | 324 ± 92 | 575 ± 77 | 1055 ± 47 | 980 ± 93 | 830 ± 141 | 7736 ± 2081 | 896 ± 140 | 378 ± 80* |
CHR | 782 ± 221 | 467 ± 63 | 1580 ± 71* | 1234 ± 117 | 685 ± 116 | 9188 ± 2472 | 1961 ± 306 | 1131 ± 240 |
WD | 410 ± 116 | 284 ± 38* | 1012 ± 46 | 757 ± 72 | 1245 ± 212 | 5476 ± 1473 | 632 ± 99 | 973 ± 206 |
Hippocampus | ||||||||
CON | 183 ± 34 | 1959 ± 402 | 2561 ± 597 | 1248 ± 124 | 3691 ± 993 | 957 ± 257 | 2457 ± 383 | 1251 ± 133 |
AC | 562 ± 103* | 1097 ± 225 | 1349 ± 314 | 808 ± 80 | 4410 ± 1186 | 1536 ± 413 | 1188 ± 185 | 690 ± 73 |
CHR | 266 ± 49 | 1545 ± 317 | 2023 ± 471 | 1821 ± 180 | 4980 ± 1340 | 1930 ± 519 | 1343 ± 210 | 1167 ± 124 |
WD | 103 ± 19 | 1033 ± 212 | 1842 ± 429 | 1761 ± 174 | 8267 ± 2224 | 2000 ± 538 | 1516 ± 236 | 1379 ± 146 |
Piriform cortex | ||||||||
CON | 609 ± 121 | 860 ± 127 | 1324 ± 207 | 1100 ± 155 | 4284 ± 878 | 1576 ± 345 | 1856 ± 380 | 1203 ± 383 |
AC | 360 ± 71 | 1464 ± 217 | 0 | 2872 ± 405* | 1055 ± 216* | 822 ± 180 | 592 ± 121* | 256 ± 81* |
CHR | 131 ± 26* | 515 ± 76 | 1104 ± 172 | 584 ± 82 | 2821 ± 578 | 824 ± 180 | 865 ± 177 | 359 ± 114* |
WD | 235 ± 47 | 176 ± 26 | 1268 ± 198 | 888 ± 125 | 2921 ± 599 | 967 ± 212 | 610 ± 125* | 203 ± 65* |
Nucleus accumbens | ||||||||
CON | 787 ± 83 | 3731 ± 302 | 17,232 ± 2188 | 0 | 0 | 1385 ± 392 | 1437 ± 162 | 583 ± 111 |
AC | 506 ± 54 | 1673 ± 136 | 12,653 ± 1607 | 0 | 0 | 948 ± 268 | 768 ± 87 | 300 ± 57 |
CHR | 394 ± 42 | 1304 ± 106* | 5570 ± 707* | 0 | 0 | 861 ± 244 | 627 ± 71 | 445 ± 85 |
WD | 88 ± 9** | 486 ± 39* | 3792 ± 482* | 0 | 0 | 162 ± 46 | 207 ± 23* | 95 ± 18* |
Entorhinal cortex | ||||||||
CON | 63 ± 13 | 436 ± 38 | 903 ± 121 | 652 ± 83 | 3511 ± 572 | 1497 ± 222 | 1461 ± 346 | 581 ± 86 |
AC | 214 ± 45 | 657 ± 58 | 749 ± 100 | 803 ± 102 | 1770 ± 289 | 816 ± 121 | 656 ± 155 | 397 ± 59 |
CHR | 244 ± 52 | 1275 ± 112* | 2017 ± 270 | 1052 ± 134 | 3271 ± 533 | 1913 ± 283 | 1052 ± 249 | 1005 ± 149 |
WD | 312 ± 66* | 1269 ± 112* | 1613 ± 216 | 1661 ± 211 | 6523 ± 1063 | 1763 ± 261 | 1424 ± 337 | 940 ± 139 |
Striatum | ||||||||
CON | 1724 ± 207 | 1992 ± 294 | 667 ± 66 | 1448 ± 226 | 983 ± 153 | 9623 ± 1155 | 2316 ± 113 | 2363 ± 250 |
AC | 534 ± 64 | 1565 ± 232 | 1522 ± 151 | 1280 ± 200 | 2642 ± 412 | 9292 ± 1115 | 1071 ± 52 | 1373 ± 145 |
CHR | 2718 ± 326 | 401 ± 59* | 1781 ± 176 | 764 ± 119 | 2205 ± 344 | 14,840 ± 1781 | 2720 ± 133 | 1459 ± 155 |
WD | 2091 ± 251 | 717 ± 106* | 2916 ± 289* | 1983 ± 309 | 1227 ± 191 | 14,663 ± 1760 | 2086 ± 102 | 2154 ± 228 |
Medulla oblongata | ||||||||
CON | 2187 ± 372 | 492 ± 45 | 5377 ± 645 | 28,807 ± 3860 | 1555 ± 308 | 1908 ± 500 | 12,443 ± 2551 | 2087 ± 399 |
AC | 3269 ± 556 | 347 ± 32 | 2263 ± 272* | 1709 ± 229*** | 58,005 ± 11,485* | 2335 ± 612 | 2087 ± 428** | 915 ± 175* |
CHR | 4269 ± 726 | 1562 ± 144* | 1293 ± 155** | 1938 ± 260*** | 47,265 ± 9359* | 2390 ± 626 | 2133 ± 437** | 715 ± 137* |
WD | 1916 ± 326 | 172 ± 16 | 1550 ± 186** | 1967 ± 264*** | 38,788 ± 7680* | 1147 ± 301 | 1312 ± 269** | 355 ± 68** |
Cerebellum | ||||||||
CON | 1636 ± 128 | 332 ± 24 | 3747 ± 502 | 2328 ± 247 | 11,040 ± 1557 | 3041 ± 988 | 2845 ± 321 | 2064 ± 584 |
AC | 1539 ± 120 | 559 ± 40 | 2461 ± 330 | 2118 ± 225 | 10,117 ± 1426 | 2070 ± 673 | 1881 ± 213 | 1004 ± 284 |
CHR | – | – | – | – | – | – | – | – |
WD | 2200 ± 172 | 1020 ± 72 | 4710 ± 631 | 2070 ± 219 | 10,320 ± 1455 | 2220 ± 722 | 5660 ± 640 | 1480 ± 419 |
Anterior | Cingulate | |||||||
---|---|---|---|---|---|---|---|---|
CON | 313 ± 31 | 2352 ± 315 | 684 ± 150 | 579 ± 115 | 1769 ± 276 | 993 ± 337 | 997 ± 254 | 385 ± 76 |
AC | 178 ± 18 | 545 ± 73* | 895 ± 196 | 1055 ± 209 | 1945 ± 303 | 666 ± 226 | 544 ± 139 | 240 ± 48 |
CHR | 202 ± 20 | 776 ± 104 | 1076 ± 236 | 750 ± 149 | 2009 ± 313 | 722 ± 245 | 934 ± 238 | 586 ± 116 |
WD | 207 ± 20 | 398 ± 53** | 700 ± 153 | 536 ± 106 | 1387 ± 216 | 200 ± 68 | 663 ± 169 | 223 ± 44 |
Posterior | Cingulate | |||||||
---|---|---|---|---|---|---|---|---|
CON | 27 ± 6 | 521 ± 100 | 1967 ± 209 | 912 ± 187 | 4697 ± 766 | 1676 ± 629 | 1217 ± 207 | 353 ± 77 |
AC | 138 ± 28* | 944 ± 180 | 1319 ± 140 | 885 ± 181 | 3286 ± 536 | 976 ± 366 | 950 ± 162 | 943 ± 207 |
CHR | 197 ± 40* | 1486 ± 284 | 1659 ± 176 | 1093 ± 224 | 4470 ± 729 | 1465 ± 549 | 1151 ± 196 | 753 ± 165 |
WD | 116 ± 24 | 1403 ± 268 | 1616 ± 172 | 1818 ± 373 | 13,661 ± 2227 | 1776 ± 666 | 1870 ± 318 | 676 ± 148 |