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Fig. 3 | BMC Neuroscience

Fig. 3

From: Detection of neuronal OFF periods as low amplitude neural activity segments

Fig. 3

MUA LA segments associated with slow-wave activity in LFP. A Layer 5 LFP corresponding with LA segments in each vigilance state. Composite image of LFP traces converted to heatmap (higher colour saturation = higher density) overlaid with mean ± SEM. Segment time range = onset -100 ms to onset + 300 ms. B Global distributions of the LFP (2–6 Hz) phase corresponding to LA segment ONSET (bottom) and END (top) in each vigilance state. Example of a sinusoid wave overlaid for visualization purposes only. C Distribution of preferred LFP (2–6 Hz) phase corresponding to LA segment ONSET and END in each vigilance state (proportion) with mean resultant vector. D Effect of state on peak amplitude in LFP corresponding to LA segments. E Relationship between LA segment duration and peak amplitude of corresponding LFP. Least-squares regression line and significant Pearson correlation coefficient shown. Black/grey = NREM, green = REM, blue = WAKE. N = 7. Mean ± SEM. Significance of effects assessed using one-way repeated measures ANOVA followed by post-hoc pairwise t-tests with Bonferroni correction (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001)

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