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Fig. 4 | BMC Neuroscience

Fig. 4

From: Detection of neuronal OFF periods as low amplitude neural activity segments

Fig. 4

LA segments are homeostatically regulated. A Relationship between LA segment occupancy and time during NREM sleep between ZT6 and ZT12 on baseline (BL) and sleep deprivation (SD) days (30 min bins). Occupancy values reported as seconds of LA segments per minute of NREM. B Change in LA segment duration during NREM sleep between ZT6 and ZT12 on BL and SD days (30 min bins). C Relationship between LA segment duration and the change in LA segment incidence between BL and SD days during the 1st hour after sleep deprivation. A change > 0 describes an increase in incidence with the sleep deprivation treatment. D Relationship between LA segment incidence and time during NREM sleep between ZT6 and ZT12 on the sleep deprivation day as a function of LA segment duration. Circles denote mean incidence and lines show least-square regression for each duration category. N = 7i. Mean ± SEM. Significance of effects assessed using two-way repeated measures ANOVA followed by post-hoc pairwise t-tests with Bonferroni correction (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001). Only significant Pearson correlation coefficients shown. i One animal lacked LA segments < 50 ms for at least one time bin so was not included in the analysis for this group of segments in D

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