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Fig. 7  | BMC Neuroscience

Fig. 7 

From: Detection of neuronal OFF periods as low amplitude neural activity segments

Fig. 7 

 LA segment detection pipeline. Example of LA segment detection stages from a 3 s segment of layer 6 baseline day recording. A Local field potential (LFP) trace (0.5–100 Hz filtered). Note the appearance of slow waves following the transition from wake to non-REM sleep. B Raw decimated multi unit activity (MUA). C Standardised MUA whereby the raw signal is converted to absolute amplitude and then the mean of the absolute MUA during clean wake epochs from this 24 h recording is subtracted. The horizontal black line marks the new mean amplitude (0 μV). Each contiguous sequence of points below this line has been recoloured alternate shades of pink. These zero crossings represent the population of possible LA segments to be investigated. A black dot demarcates the centre of each zero crossing. D Standardised MUA with low amplitude cluster points recoloured red. E Raw MUA with final LA segments recoloured red. Final LA segments represent zero crossings which intersect with low amplitude cluster points. Black dots represent the centre of each LA segment

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