- Poster presentation
- Open Access
Global network community and non-uniform cell density in the macaque brain
© Shimono; licensee BioMed Central Ltd. 2014
- Published: 21 July 2014
- Cell Density
- Topological Characteristic
- Fiber Tract
- Network Measure
- Neuron Density
The important question, how the global network architecture connecting cortical regions keeps balances between integration and segregation of information processes, have been asked to understand the design of the brain [1, 2]. This study aimed to clarify how topological characteristics of such global network architecture relate with physiological characteristics inside of segmented cortical regions in the monkey brain . Especially, I focused on cell densities (densities of neurons or non-neurons) as the representative characteristics of segmented cortical regions , and compared the cell densities with network topologies of cortico-cortical fiber tracts [Figure1-A]. To reduce biases in comparisons, I surveyed many topological measures as wide as possible. Total number of evaluated network measures was 27.
M.S. is grateful to Yasuo Kawaguchi, John M. Beggs, and Olaf Sporns for their important discussions. This study was supported by a Grant-in-Aid for JSPS Fellows for Research Abroad.
- Chen Y, Wang S, Hilgetag CC, Zhou C: Trade-off between Multiple Constraints Enables Simultaneous Formation of Modules and Hubs in Neural. PLoS computational biology. 2013, 9 (3): e1002937-10.1371/journal.pcbi.1002937.PubMed CentralView ArticlePubMedGoogle Scholar
- Sporns O: Network attributes for segregation and integration in the human brain. Current opinion in neurobiology. 2013Google Scholar
- Shimono M: Non-uniformity of cell density and networks in the monkey brain. Scientific reports. 2013, 3:Google Scholar
- Collins CE, Airey DC, Young NA, Leitch DB, Kaas JH: Neuron densities vary across and within cortical areas in primates. Proc Natl Acad Sci USA. 2010, 107 (36): 15927-15932. 10.1073/pnas.1010356107.PubMed CentralView ArticlePubMedGoogle Scholar
- Cahalane DJ, Charvet CJ, Finlay BL: Systematic, balancing gradients in neuron density and number across the primate isocortex. Frontiers in Neuroanatomy. 2012, 6: 28 -PubMed CentralView ArticlePubMedGoogle Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.